Products

L-Ascorbyl-2-Phosphate

    • Product Name: L-Ascorbyl-2-Phosphate
    • Chemical Name (IUPAC): (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one 2-(dihydrogen phosphate)
    • CAS No.: 66170-10-3
    • Chemical Formula: C6H9O9P
    • Form/Physical State: Solid
    • Factroy Site: No. 1, Qiyuan Avenue, Wangyuan Industrial Park, Yongning County, Ningxia
    • Price Inquiry: sales7@bouling-chem.com
    • Manufacturer: Ningxia Qiyuan Pharmaceutical Co., Ltd
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    Specifications

    HS Code

    708424

    Cas Number 85801-77-8
    Molecular Formula C6H9O9P
    Molecular Weight 270.11 g/mol
    Synonyms L-Ascorbic acid 2-phosphate, Vitamin C 2-phosphate
    Appearance White to off-white powder
    Solubility In Water Freely soluble
    Ph Of 1 Solution 2.0 - 3.0
    Storage Condition Store at 2-8°C, protected from light
    Stability More stable than ascorbic acid in solution
    Usage Used as an antioxidant and as a vitamin C supplement in cell culture media

    As an accredited L-Ascorbyl-2-Phosphate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The chemical `L-Ascorbyl-2-Phosphate` is packaged in a sealed 100g amber glass bottle with a secure screw cap.
    Container Loading (20′ FCL) 20′ FCL container loading for L-Ascorbyl-2-Phosphate: typically packed in 25kg drums, totaling 10,000kg per 20′ FCL.
    Shipping L-Ascorbyl-2-Phosphate is shipped in tightly sealed containers to protect it from moisture and light. The chemical is typically packed in cool, dry conditions and labeled in accordance with regulatory guidelines. Appropriate documentation accompanies the shipment to ensure safe handling, transport, and compliance with national and international shipping regulations.
    Storage L-Ascorbyl-2-Phosphate should be stored in a tightly sealed container, protected from light and moisture. Store at 2–8°C (refrigerator temperature) for optimal stability. Avoid exposure to heat and direct sunlight. Handle under inert atmosphere if possible to prevent oxidation. Keep away from incompatible substances such as strong oxidizing agents. Proper labeling and handling are recommended to ensure safety and integrity.
    Shelf Life L-Ascorbyl-2-Phosphate typically has a shelf life of 2–3 years when stored cool, dry, and protected from light and moisture.
    Application of L-Ascorbyl-2-Phosphate

    Purity 99%: L-Ascorbyl-2-Phosphate with purity 99% is used in cosmetic formulations, where it provides enhanced skin brightening and antioxidation stability.

    Molecular Weight 322.2 g/mol: L-Ascorbyl-2-Phosphate of molecular weight 322.2 g/mol is used in dermatological serums, where it offers targeted, efficient cellular uptake.

    Stability temperature up to 70°C: L-Ascorbyl-2-Phosphate with stability temperature up to 70°C is used in heat-processed skincare emulsions, where it ensures sustained antioxidant activity during formulation.

    Particle Size <10 μm: L-Ascorbyl-2-Phosphate with particle size below 10 μm is used in topical creams, where it promotes uniform dispersion and fast absorption.

    Water Solubility >50 g/L: L-Ascorbyl-2-Phosphate with water solubility above 50 g/L is used in aqueous vitamin supplements, where it delivers high bioavailability and rapid dissolution.

    pH Stability 5.5–8.0: L-Ascorbyl-2-Phosphate with pH stability from 5.5 to 8.0 is used in multi-phase skincare systems, where it retains efficacy in diverse formulations.

    Heavy Metals <10 ppm: L-Ascorbyl-2-Phosphate with heavy metals content below 10 ppm is used in pharmaceutical injectables, where it minimizes contamination risk and meets regulatory standards.

    Residue on Ignition <0.1%: L-Ascorbyl-2-Phosphate with residue on ignition below 0.1% is used in nutritional supplements, where it assures high product purity and safety.

    Melting Point >200°C: L-Ascorbyl-2-Phosphate with melting point above 200°C is used in high-temperature manufacturing processes, where it maintains structural integrity and activity.

    UV Absorbance at 265 nm: L-Ascorbyl-2-Phosphate with UV absorbance at 265 nm is used in analytical quality control, where it enables precise detection and quantification.

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    Certification & Compliance
    More Introduction

    L-Ascorbyl-2-Phosphate: A Manufacturer’s Perspective

    Understanding L-Ascorbyl-2-Phosphate

    Every chemist in our production team knows the difference a stable form of vitamin C can make in consumer and industrial applications. Over years of manufacturing, we have observed L-Ascorbyl-2-Phosphate consistently outperforming standard ascorbic acid in stability and versatility, especially under challenging formulation conditions. As a manufacturer, we work at the source – from raw material procurement through precise reactor conditions to the latest automated purification lines – to deliver a high-purity product that remains true to both its technical role and regulatory requirements.

    Our process generates L-Ascorbyl-2-Phosphate (model code SAP-35) as a fine, free-flowing white crystalline powder, with an assay above 98%. The method we follow steers clear of excess exposure to moisture and heat, and this careful control at each stage ensures a consistently high level of active material across batches. This stability under light, heat, and oxygen exposure sets it apart for specialists in personal care, animal feed, and specialized health formulations.

    Why a Manufacturer Focuses on Real-World Performance

    Clients from cosmetic labs and feed mills often visit our plant and talk at length about formulation headaches with ascorbic acid. Standard vitamin C doesn’t always hold up; it breaks down quickly in water-based environments and loses activity before it even reaches the end user. Running repeated stability trials in our analytical labs, we have documented L-Ascorbyl-2-Phosphate’s solid resistance to oxidation and pH extremes, meeting the needs that ascorbic acid simply cannot.

    Our colleagues in the production hall see up close how trace metals and pH excursions can damage ascorbic acid batches. L-Ascorbyl-2-Phosphate brings real improvement: its phosphate group shields the molecule, creating bigger windows for stable inclusion in aqueous, high-pH, and even peroxide-rich solutions. This isn’t theoretical. Our shipping department tracks less spoilage and fewer returns from partners using SAP-35 than any regular ascorbic acid or sodium ascorbate shipment.

    This ingredient also carries high value for feed manufacturers. Veterinary clients, particularly those who formulate fortified aquatic and specialty feeds, tell us about the rapid breakdown of vitamin C in storage and processing. In response, our R&D group regularly demonstrates SAP-35’s recovery after intensive pelleting and extrusion trials. The phosphate modification shows better survivability across exposure to pressure and heat, resulting in higher bioavailable vitamin concentration in the finished product.

    Meeting the Needs of the Cosmetics Industry

    The global skin care market pushes us to develop actives with genuine stability. Early tests in our applications lab saw traditional ascorbic acid creams quickly yellowing, losing potency in a matter of days. Our chemists, in cooperation with cosmetic customers, have seen L-Ascorbyl-2-Phosphate deliver more reliable ascorbic acid release on the skin, longer shelf life, and successful passage through stability testing under varied storage conditions.

    Cosmetic formulators repeatedly highlight how SAP-35 tolerates a wider formulation pH range. Our lab data shows that typical vitamin C solutions degrade at pH above 4. L-Ascorbyl-2-Phosphate, because of the phosphate ester, remains intact up to pH 7 and slightly above, allowing broader choices in product texture and type. No longer do formulators need to fight the acidification that standard ascorbic acid causes in gels, foams, and lotions.

    Skin care specialists often come to our technical support center asking for ways to combine vitamin C with common actives like niacinamide or peptides. Traditional ascorbic acid simply fails in these complex blends. Our in-house experiments demonstrate that SAP-35 stands up to these challenges. It provides a reliable foundation for brightening and antioxidant blends – and our customers confirm fewer product returns and better consumer feedback.

    Animal Nutrition: Making Every Gram Count

    Feed manufacturers always struggle with micronutrient losses in high-temperature processing. Ascorbic acid may be affordable, but much is lost before an animal ever consumes the finished feed. Through close work with livestock feed partners, we have verified that L-Ascorbyl-2-Phosphate dramatically improves retained vitamin C content through extrusion and long storage.

    Through in-house feed processing trials, we have compared SAP-35 side by side with unmodified ascorbic acid and sodium ascorbate. Under pressurized steam and heat, native ascorbic acid typically drops in measured content by 30-40%. SAP-35 losses remain below 10%. This improvement is not just quantifiable at the manufacturing level; producers notice improved health and growth rates in animals, especially in stressful production systems or high-density aquaculture environments.

    In our role as a direct manufacturer, we also address solubility issues that many in the feed sector notice with other vitamin C derivatives. L-Ascorbyl-2-Phosphate dissolves easily in water, making post-pellet spraying and liquid-feed supplementation efficient. Minimal sediment reduces the waste observed in tanks, and active levels remain closer to label values for longer storage periods.

    Pharmaceutical Formulation and Medical Uses

    Pharmaceutical research groups often request a source of vitamin C stable in both solid and liquid preparations, suitable for oral and parenteral products. Over the last decade, our technical service department has worked with international partners conducting stability studies under pharmacopeial protocols. In tablets and granulates, L-Ascorbyl-2-Phosphate shows better preservation of potency – a strong improvement in meeting regulatory shelf-life targets.

    Our pharmaceutical customers frequently update us about their challenges with degradation products in vitamin C supplements. Dehydroascorbic acid, the main breakdown product of native ascorbic acid, accumulates quickly under common storage conditions. This results in product failures and difficult conversations with regulatory inspectors. Several clients adopting SAP-35 have shared internal data linking its use with higher final product release success and fewer out-of-specification cases.

    Medical nutrition formulators, especially those producing tube-feeding solutions, also find that L-Ascorbyl-2-Phosphate provides the stability required for modern, multi-use packaging formats. Our own lab tests back up their claims, with preserved vitamin content during shelf-life simulations far surpassing results from ascorbic acid controls.

    Quality and Manufacturing Process Details

    Years of investment in state-of-the-art production lines pay off during the tricky steps from raw phosphate-derivatization to purification. Our ongoing monitoring program tracks temperature, pH, and agitation speed at every stage. Chemists and plant operators communicate in real time, correcting any deviation before the next batch proceeds. This hands-on approach results in SAP-35 meeting not only in-house QC but also external third-party certifications without deviation.

    Batch consistency and low heavy metal content do not just come from clean starting materials. The strictness of our manufacturing controls keeps final sample readings for impurities reliably below industry thresholds. As finished product leaves our drying and packing area, it passes through metal detectors and optical checks. Our technical staff validate every lot for shelf stability and solubility – the real-world tests that matter most to downstream formulators.

    This level of control grants SAP-35 outstanding clarity and performance in demanding applications. We see lower customer complaint rates, longer product shelf lives, and repeat orders from manufacturers who have already tested competitors’ material but faced variable results.

    Comparing L-Ascorbyl-2-Phosphate to Other Vitamin C Derivatives

    Having processed and tested many vitamin C derivatives, we know that not every solution fits every purpose. Sodium Ascorbyl Phosphate and Magnesium Ascorbyl Phosphate have their roles, but they frequently suffer from higher cost structures, less dependable pH range, and different solubility behaviors. Some users prefer SAP-35 for its balance of stability, ease of use, and consistent results.

    Basic ascorbic acid may appeal for its price and rapid bioavailability in some applications. Even so, it brings hassle: practitioners face much faster oxidation, yellowing, and a need for acidified environments. For ingredients like Ascorbyl Palmitate, manufacturers often report problems with oil-solubility and inconsistent incorporation into water-based products. In contrast, SAP-35 works seamlessly in both dry premixes and aqueous or gel-based systems.

    Over years of technical service calls, it’s become clear that customers return to SAP-35 due to its clean sensory profile – low odor, no taste impact, and no visible particulate. Formulators save time because the raw material flows and mixes effortlessly, with minimal operator adjustment. Our partners see higher throughput and lower batch rejects, a direct result of reliable ingredient handling.

    From our own field research, SAP-35 scales up well. Unlike some alternatives, it provides a direct, one-to-one vitamin C equivalent, making dosing calculations straightforward for both small- and industrial-scale formula adjustments. End users appreciate that the phosphate bond protects the molecule up until it enters a biological system, where enzymatic action rapidly releases active ascorbic acid—an effect seen both in animal trials and clinical tests shared by our clients.

    Regulatory Confidence and Traceability

    As manufacturers, we face constant, direct scrutiny from inspectors, whether for FAMI-QS, GMP, or local regulatory schemes. Our document trails for SAP-35 ingredients start from supplier qualification through in-process control logs to every batch certificate. International customers in regions with complex import controls depend on our detailed traceability; missing just one piece of paperwork can mean months of delay. Our regulatory affairs team keeps in close contact with both auditors and customers to streamline the process.

    Certifying the absence of harmful residues and confirming compliance with food safety laws is not optional for us. We regularly submit production and finished product samples for third-party analysis to confirm our readings. Having seen competitors caught out during import checks or audits, our operations prioritize redundancy in testing and record-keeping. We’ve witnessed first-hand how a single incident of contamination can undermine years of brand equity for both supplier and downstream client.

    Supply Chain Realities and Batch Customization

    As an actual manufacturer, sourcing impacts quality as much as what happens within our walls. Over the last decade, shortages in phosphate esters and vitamin C intermediates have put pressure on timelines and costs. Working directly with upstream chemical processors grants more predictability and enables us to forecast price changes and potential lead times for customers. Our logistics coordinators manage direct-to-client shipping, bypassing unnecessary handoffs and reducing risks of contamination or repackaging errors.

    Some customers require non-standard mesh sizes, higher-pack weights, or different packaging barrier systems. With our vertically integrated operation, new batch customization remains possible, with R&D, QC, and packaging teams sitting quite literally across the hallway from one another. Adjustments – from particle sizing to printed packaging lots – are implemented within weeks, not months. This agility gives our partners a market edge, especially when launching new or seasonal formulations.

    Environmental Responsibility from the Manufacturer’s Standpoint

    Sustainability has become more than a boardroom talking point in chemical production. Strict wastewater controls and responsible handling of spent reagents ensure we operate well within environmental thresholds. Upgrades to our effluent management and solvent recovery plants have reduced water use and minimized waste output. Decisions here come not only from compliance drives but from actual on-the-ground experience; it costs everyone – supplier, client, and local community – when corners are cut.

    We recycle packaging where possible, send all off-spec products through dedicated destruction channels, and conduct regular staff training in environmental health and safety. Chemical production looks different compared to a generation ago, and as regulatory and market pressure grows, we maintain our systems ahead of most global standards.

    What Industry Users Say and Where SAP-35 Fits Best

    Downstream customers in cosmetics often relay to us improved consumer loyalty and lower rates of product returns after switching to L-Ascorbyl-2-Phosphate. They share market feedback about clearer, brighter creams with longer shelf stability, and lower regulatory hassle in diverse geographies.

    Feed makers note measurable health improvement in their animal herds, especially where harsh climates or long-chain shipment complicate animal nutrition. Data from field trials, later published by animal health authorities, matches what we see in our in-house testing.

    Pharmaceutical partners value the direct line to the actual production floor. Their formulation queries are answered with real-time access to our technical team, not through third-party translation. They tell us about reducing costly reformulations and compliance headaches.

    Continuous Improvement Driven by Real Experience

    Ongoing feedback loops between our customers, laboratory, and production lines have reshaped how we make and support SAP-35 over the years. Not a month passes without an update from technical staff, automating a bottleneck, revising a stability protocol, or tweaking a production step. Every improvement, no matter how small, impacts the supply chain and end user.

    In direct customer meetings, we listen openly to process and product complaints. Issues surface faster when a manufacturer handles hundreds of metric tons annually, and our proximity to the process lets us investigate, correct, and prevent recurring issues. These lessons learned translate into fewer delays, lower running costs, and greater consistency in every delivered lot.

    L-Ascorbyl-2-Phosphate’s Role in Industry: Manufacturer’s Outlook

    Access to reliable, shelf-stable vitamin C makes all the difference in modern personal care, animal nutrition, and pharmaceutical products. Standard ascorbic acid simply can’t deliver what complex formulations now require. L-Ascorbyl-2-Phosphate, through its chemical structure and real-world production advantages, stands as the ingredient that bridges these demands.

    Our ongoing investment in both process control and customer-facing support has entrenched SAP-35’s role across applications that other ingredients cannot fill. As a direct manufacturer, our responsibility lies not just in making the powder, but in embedding our expertise in every shipment; feedback, field trial, and regulatory review strengthens the quality of future lots. This connection to every layer of production – and to each customer’s unique challenges – ensures that SAP-35 remains a pillar vitamin C source for changing industry needs.