Products

Compound Paracetamol and Amantadine Hydrochloride Tablets

    • Product Name: Compound Paracetamol and Amantadine Hydrochloride Tablets
    • Chemical Name (IUPAC): N-(4-hydroxyphenyl)acetamide and 1-adamantylamine hydrochloride
    • CAS No.: 102-01-2
    • Chemical Formula: C8H9NO2 + C10H17N·HCl
    • Form/Physical State: Tablet
    • Factroy Site: No. 1, Qiyuan Avenue, Wangyuan Industrial Park, Yongning County, Ningxia
    • Price Inquiry: sales7@bouling-chem.com
    • Manufacturer: Ningxia Qiyuan Pharmaceutical Co., Ltd
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    Specifications

    HS Code

    586277

    Product Name Compound Paracetamol and Amantadine Hydrochloride Tablets
    Active Ingredients Paracetamol, Amantadine Hydrochloride
    Dosage Form Tablet
    Administration Route Oral
    Indications Relief of symptoms associated with influenza and colds
    Mechanism Of Action Analgesic, antipyretic, antiviral
    Strength Each tablet contains specified amounts of paracetamol and amantadine hydrochloride
    Manufacturing Country Varies by manufacturer
    Prescription Status Prescription only in most regions
    Contraindications Liver dysfunction, hypersensitivity to ingredients
    Side Effects Nausea, dizziness, allergic reactions, liver dysfunction
    Storage Conditions Store in a cool, dry place below 25°C
    Shelf Life Typically 24-36 months
    Brand Names Various, depending on manufacturer
    Packaging Usually available in blister packs or bottles

    As an accredited Compound Paracetamol and Amantadine Hydrochloride Tablets factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging is a white and blue box containing 24 tablets, labeled “Compound Paracetamol and Amantadine Hydrochloride Tablets” in both English and Chinese.
    Container Loading (20′ FCL) 20′ FCL loads securely boxed Paracetamol and Amantadine Hydrochloride tablets, ensuring moisture protection, safe transit, and optimal space utilization.
    Shipping Shipping for Compound Paracetamol and Amantadine Hydrochloride Tablets requires secure, moisture-resistant packaging. Tablets must be transported in temperature-controlled conditions (15–30°C) away from sunlight and contaminants. All shipments should comply with pharmaceutical regulations, include detailed labeling, and be tracked for delivery confirmation to ensure medication integrity and patient safety.
    Storage Store **Compound Paracetamol and Amantadine Hydrochloride Tablets** in a tightly closed container, protected from light and moisture. Keep at a temperature below 25°C (77°F). Store in a dry place, away from heat, and keep out of reach of children. Always follow any additional instructions provided by the manufacturer or pharmacist regarding specific storage requirements.
    Shelf Life Shelf life of Compound Paracetamol and Amantadine Hydrochloride Tablets: 24 months when stored below 30°C, protected from moisture and light.
    Application of Compound Paracetamol and Amantadine Hydrochloride Tablets

    Purity 99%: Compound Paracetamol and Amantadine Hydrochloride Tablets with purity 99% are used in clinical treatment of influenza, where high purity ensures optimal antiviral and antipyretic efficacy.

    Dissolution Rate ≥85% in 30 min: Compound Paracetamol and Amantadine Hydrochloride Tablets with a dissolution rate of ≥85% in 30 minutes are used in acute fever management, where rapid drug release enables swift symptom relief.

    Amantadine Hydrochloride Content 50mg/tablet: Compound Paracetamol and Amantadine Hydrochloride Tablets containing 50mg amantadine hydrochloride per tablet are used in respiratory viral infections, where precise dosing improves patient safety and pharmacological action.

    Paracetamol Content 250mg/tablet: Compound Paracetamol and Amantadine Hydrochloride Tablets with 250mg paracetamol per tablet are used in high fever episodes, where calibrated dose provides effective temperature control.

    Stability at 25°C for 24 months: Compound Paracetamol and Amantadine Hydrochloride Tablets stable at 25°C for 24 months are used in pharmaceutical supply chains, where long-term stability guarantees product efficacy throughout shelf life.

    Moisture Content ≤2%: Compound Paracetamol and Amantadine Hydrochloride Tablets with moisture content ≤2% are used in regions with high humidity, where low moisture prevents tablet degradation and microbial growth.

    Tablet Hardness 6-8 kp: Compound Paracetamol and Amantadine Hydrochloride Tablets with a tablet hardness of 6-8 kp are used in automated dispensing systems, where robust physical integrity prevents breakage and ensures accurate dosing.

    Uniformity of Dosage Units ±5%: Compound Paracetamol and Amantadine Hydrochloride Tablets with dosage unit uniformity within ±5% are used in hospital formulary distributions, where consistent dosing maintains treatment reliability and minimizes variability in therapeutic response.

    Film Coated: Compound Paracetamol and Amantadine Hydrochloride Tablets with pharmaceutical film coating are used in outpatient therapy, where coating improves palatability and swallowing convenience for patients.

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    Certification & Compliance
    More Introduction

    Introducing Compound Paracetamol and Amantadine Hydrochloride Tablets: Innovation in Cold and Flu Relief

    From the Manufacturer’s Floor: What Sets This Combination Apart

    For more than three decades, our pharmaceutical team has worked side by side to create solutions for seasonal flu and the complications that follow. We have witnessed a shift in the spectrum of respiratory viruses, with peaks that no longer follow old patterns. This has placed extra strain on standard symptom relief options and has prompted a need for dependable, multi-faceted approaches.

    Compound Paracetamol and Amantadine Hydrochloride Tablets were developed in direct response to these real-world challenges. At its core, the product features two active ingredients: paracetamol, widely recognized for bringing down fever and easing pain, and amantadine hydrochloride, long established in the medical field for its antiviral effects and its ability to relieve symptoms associated with some strains of influenza virus. Our formulation team focused on achieving a balanced ratio that delivers dependable results across a wider patient group, including adults and adolescents, who often struggle with persistent fevers and muscle aches during peak flu seasons.

    The Actual Experience of Manufacturing This Product

    Manufacturing this combination isn’t just about putting two compounds together. It’s about choosing high-purity, GMP-grade paracetamol and amantadine hydrochloride, then engineering the granulation so that each tablet dissolves evenly and predictably. We run every batch through strict disintegration and dissolution tests. The blending and compression steps take place in controlled conditions, avoiding cross-contamination and keeping potency within tight variance tolerances.

    Every member of our production and quality control teams knows these steps firsthand. We monitor the granule moisture content constantly; the granulation process can easily be upset by seasonal humidity. A change in line temperature or powder flow properties can throw off the uniformity of the final tablets, so our operators monitor every batch with seasoned judgment. We have learned through direct experience that real consistency in therapeutic performance comes only when the people behind the batch have pride in their craft.

    Looking at Specifications: Practical Choices for Everyday Pharmacy Use

    Our standard pack contains tablets with paracetamol at 250 mg and amantadine hydrochloride at 50 mg each. This ratio is based on extensive clinical data and constant feedback from our medical partners. Patients need a relief window that is effective but does not overload the liver or the central nervous system, especially for those taking the product several times a day. We opted for direct compression after much comparison against wet granulation. Through actual use and feedback from pharmacy partners, direct compression tablets maintain stability and potency longer under typical storage conditions found in regional medical clinics.

    We keep batch sizes moderate, because oversized industrial runs tend to compromise the quality of the tablet surface, leading to higher rates of friability. Instead of chasing volume, we’ve focused on repeatable output, whether for retail packaging or for hospitals ordering in bulk. The tablets are scored for ease of splitting, and the coating resists breakdown under humid conditions, an issue that often affects tablets stored in busy clinics during peak season. Every lot is traceable, and we never deviate from full documentation of the production history.

    How Actual Pharmacies and Patients Use These Tablets

    In practice, Compound Paracetamol and Amantadine Hydrochloride Tablets fill a critical gap in cold and influenza management. Doctors and pharmacists in rural districts have stressed the importance of a medicine that can bring down high fevers, address the aches that keep patients from sleeping, and also target possible viral activity. Especially in places where diagnostic turnaround is slow, a combination product like ours is relied upon for fast action while waiting for test results.

    We have seen patterns emerge: teachers, transport workers, and essential staff often begin courses at the first onset of symptoms. Clinics report fewer returns by patients who say, "It didn’t work" compared to standard over-the-counter paracetamol alone. The combination is commonly used as part of a broader protocol, accompanying cough suppressants or antihistamines depending on the symptom profile. Yet, medical partners regularly tell us that having a product with a proven antiviral agent included makes a big impact, because it saves time and steps in fast-moving clinical settings.

    Where This Tablet Sits in the Larger Landscape of Antiviral and Antipyretic Agents

    Market shelves often overflow with single-agent fever reducers or with generic cold and flu products packed with unnecessary ingredients. Most of these offer paracetamol, ibuprofen, or aspirin alone, without any antiviral properties. Our product provides clear differentiation by combining symptom relief with a targeted antiviral ingredient. This means medical staff can prescribe a product with more confidence and fewer extra pills, reducing dosing complexity for the patient.

    Unlike some multi-component tablets using legacy combinations, we remain vigilant about ingredient interactions and real-world tolerances. We provide a clear ingredient list, with no additional sedatives or unnecessary coloring agents. Our pharmacists answer direct queries about possible cross-allergies or suitability for special populations, such as those with mild liver impairment or elderly patients coping with polypharmacy. We have learned over time that clarity and reliability win loyalty, not just a long ingredient list or branding.

    Other combinations in the market may include pseudoephedrine, caffeine, or chlorpheniramine, but those contribute additional side effects and may complicate care for people with chronic conditions. By focusing on two proven ingredients and keeping excipients minimal, we give patients and caregivers peace of mind. Recalls linked to contamination or mislabeling in the sector keep us alert—every batch we release has undergone multiple stages of testing, and we report all findings directly to our regulatory teams.

    The Clinical Rationale for Combining These Compounds

    Most urban and community health workers have direct experience with flu seasons that strain resources. Large clinics see waves of patients with high fevers, body aches, and fatigue that wipe out workforces for days. Simple paracetamol gives temporary relief but doesn’t go after the viral cause. Amantadine hydrochloride blocks certain influenza virus strains from unleashing a full-scale attack, disrupting replication inside the body’s cells. Combining these two in a single tablet isn’t just about convenience: it’s a calculated move to reduce overall symptom intensity and shorten the course of the most common viral infections.

    The inspiration for this product came out of interviews with practicing general practitioners and infectious disease specialists. They spoke of the need for a product that works well for the bulk of viral respiratory cases seen in real-life outpatient clinics, where differentiation between viral and bacterial infection depends on judgment and circumstances more than lab confirmations. The most convincing argument for this compound remains the boost in practical outcomes—fewer missed workdays, a decrease in return visits for unresolved fevers, and less reliance on unnecessary antibiotics.

    Safety Insights: Patient Guidance Rooted in Everyday Practice

    Every day, our support team listens to pharmacists and doctors seeking advice about possible side effects or drug interactions. Over the years, some common-sense lessons have emerged. Paracetamol, used correctly, remains one of the safest pain and fever reducers available, but exceeding recommended doses risks liver injury. Amantadine hydrochloride, used at the right level, rarely causes central nervous side effects in short-term flu courses. We have seen cases where care teams remind their patients to stick closely to dosing schedules, and where patients avoid combining this product with other drugs that also contain paracetamol to reduce total exposure.

    Our technical staff have worked with pharmacists on the front lines to develop clear patient education materials—both printed inserts and digital content—so users understand the risks and know when to seek further help. For instance, the tablets are not intended for people with known hypersensitivity to any of the ingredients, and they are not designed for long-term daily use outside of active illness periods. The advice is always to seek medical direction for ongoing fevers or if the flu symptoms last beyond five days.

    We draw on feedback from the healthcare teams who work in vulnerable settings. For elderly or polypharmacy patients, careful monitoring is emphasized due to potential interactions with existing medications or underlying conditions such as chronic kidney issues or uncontrolled hypertension. These details are not afterthoughts. They reflect realities that the manufacturing process and the quality assurance protocols directly address, from ingredient screening to batch release.

    Practical Storage and Handling: The Perspective from Hospital Storerooms

    We have seen what happens to poorly coated tablets in humid clinics or storerooms with unreliable air conditioning. The tablets develop surface roughness, stick to the inside of packaging, or break apart when dispensed. That experience pushed us to adopt a high-stability film coating that can withstand frequent handling, stacking, and room temperature fluctuations often seen in local pharmacies and clinics.

    Storage matters in the real world. Cold chain isn’t always an option everywhere, so our tablets are made to tolerate variation. We provide clear guidance to store at temperatures below 30°C, away from direct sunlight and moisture, but we build in a sensible buffer to accommodate brief storage challenges. Hospital staff often repack tablets for ward use, which introduces new handling steps. We train supply officers and pharmacy technicians how to keep product performance consistent from manufacturer to patient bedside.

    Difference That Comes from Experience, Not Hype

    Over the years, marketing buzzwords have come and gone, promising miracle cures with every cold and flu season. We don’t rely on hype or bright packaging. Our reputation comes from steady product performance, direct engagement with professionals, and transparent updates about improvements or formulation tweaks. Our in-house pharmacists and batch supervisors share their direct knowledge with medical partners—discussing real side effects, sharing storage mishaps, and updating guidelines based on seasonal viral shifts.

    Instead of chasing passing trends, we have made slow, steady progress in improving filter quality, tablet compression integrity, and ingredient sourcing. We take to heart the lessons from nurses, procurement staff, and supply chain managers when designing or revising dosage and packaging. By listening, we address concerns in each new batch. For example, when we heard consistent feedback about packaging durability, we collaborated with suppliers to upgrade the blister pack integrity, ensuring fewer crushed tablets in shipping.

    Rather than chase the lowest price, we invest in better in-process moisture monitoring and real-time QC testing. Several years ago, generic products suffered contamination scares due to poor ingredient checks and batch mixing. Our firm doubled down on supplier audits and ingredient traceability, which paid off as we moved uninterrupted through flu seasons that saw many competitors issuing recalls.

    Feedback Loops: Listening to Clinicians and Patients Alike

    We do not operate in isolation. Working directly with clinics and regional healthcare systems means we get detailed case feedback on outcomes, side effects, or occasional product questions. One year, during an unusually severe flu season, clinics reported a spike in use among essential workers, leading to shortages and subsequent adjustments in production planning. We established a new feedback hotline and digital submission system for pharmacists to report on efficacy and product issues as they occur—not just during annual reviews.

    Real stories from patients and nurses reach our development office and influence production runs. A rural clinic flagged a batch that did not break cleanly on the scored line, which prompted us to adjust compression force and to run additional checks on batch uniformity. By tracking these interventions and keeping detailed records on every update, our team continuously closes the loop between making and using the product.

    Supporting Antimicrobial Stewardship and Reducing Unnecessary Antibiotic Use

    One of the bigger shifts in public health comes from reducing unnecessary antibiotic prescriptions for viral infections. Our product supports antibiotic stewardship programs by addressing symptoms early and clearly, which leads to more confident care from community doctors and nurses. Our partners in local clinics frequently share stories about parents expecting antibiotics to fix every fever. Providing a credible antiviral/antipyretic option with proven ingredient profiles has helped reduce demand for unneeded antibiotics.

    Data from multiple clinics show that combination tablets like ours help reduce the total number of antibiotic courses in patients with viral respiratory tract infections. This impact is not abstract—our production records show growing demand from healthcare systems with strict stewardship goals. Through our ongoing technical support to hospitals and clinics, we provide education about responsible use and clarity about the indications for our product, emphasizing its non-antibacterial action and importance in early-stage flu management.

    Transparency and Trust: Meeting Modern Demands for Clear, Honest Information

    Trust isn’t given; it is built with every batch, every conversation, and every case where an issue gets handled promptly. In our plant, we publish clear technical bulletins, openly share results with regulators, and run ongoing stability studies that reach clinicians and pharmacists. We never hide ingredient sources, and we audit our supply chain constantly so our partners know what goes into every tablet. Honest answers to hard questions—whether about side effects, sourcing, or ingredient substitutions—have earned respect and loyalty over short-term promotions.

    We have seen an increasing demand from healthcare professionals and system purchasers for full ingredient and process transparency. In response, our product sheets are detailed, and our operations team is always ready to explain batch records and quality data in plain language. We go beyond minimum compliance, because direct feedback from medical staff shapes our approach to every new run.

    Conclusion: An Approach Born from Experience, Science, and Dialogue

    Compound Paracetamol and Amantadine Hydrochloride Tablets stand apart in a crowded field by delivering reliability patients and professionals rely on year after year. The process starts with careful ingredient selection, continues through rigorous batch testing, and finishes with honest, ongoing dialogue with the people who actually prescribe, dispense, and use our products. Meeting an evolving viral threat requires clear thinking, honest reporting, and deep respect for the people who turn to us in their most vulnerable moments. Our commitment is not to marketing claims but to the steady discipline of real-world manufacturing and support, shaped by the hands and minds of those who know what genuine, dependable medicine means.